The workshop will take place from February 7 - February 14, 2025

This year’s workshop aims to bring ~50 researchers together to discuss challenges associated with the profiling and analyses of metagenomic microbial communities (bacterial, fungal and viral). Technologies to profile these extremely complex communities of ‘’small organisms’’ have developed very quickly and it is now routine and cost effective to sample the microbiome across a broad range of domains. The invitees this year cover domains such as the microbiome of the human gut/oral/respiratory/urogenital in the context of health and disease; clinical metagenomics; of animals in relation to food production systems; the microbiome and diet; fungal viruses; approaches for identifying new microbes. The meeting will also discuss high-throughput systems level approaches for studying microbes including genetic screens, single-cell bacterial/fungal profiling, microfluidic sample handling, improved CRISPR/CasX modification toolkits, synthetic biology along with core biostatistical computational approaches including generative modeling in microscopy, sample decomposition and compositional data (CODA) analyses.

Computational Paradigms in Molecular Biology Revisited will take place from February 2 - February 9, 2024

The past decade has witnessed the rapid development of new computational techniques and paradigms in computational biology. These approaches emerged from the machine learning, probabilistic modeling, statistical inference and artificial intelligence communities and have been further refined within the context of a broad range of applications in molecular biology. This meeting brings together researchers who have expertise with generative modeling and deep learning across a range of different applications including structural biology, drug repositioning and discovery, generative models for single cell analyses, metagenomics, and molecular imaging. Many of our invitees are also committed to the development of computational devices with clinical utility. Such endpoints also raise important ethical and socioeconomic considerations that also must be addressed for AI-related tools to be fully incorporated into modern molecular biology and clinical applications.

Cells in Space will take place from January 27th - February 3rd, 2023.

This year will be our 21st Systems Biology workshop: over the past two decades, these meetings have brought together individuals working in the diverse range of fields.

This meeting brings together researchers interested in exploring cells in their context. Recent advances have reinforced the importance of understanding where cells are localized in tissues to further characterize their similarity and differences (cell types) and shed light on their interactions, communication and functionality.

The invitees collectively champion the development and/or application of EXPERIMENTAL approaches to identify the physical location of cells based on sequencing or imaging methods, and COMPUTATIONAL models to analyze cellular information and/or predict its location.

We are excited to extend discussions to how a wide variety of external factors and stressors, such as space travel, the exposure to microgravity and space radiation, the synergistic effect of microbiomes, infection processes, tumor microenvironments, etc., influence or alter cellular expression and epigenetics programs.

Encoding an Decoding Function in the Genome. Friday February 4th to Friday February 11th, 2022

This meeting brings together researchers interested in approaches that systematically modify and perturb genomes in order

  • [DECODE] to understand the function of the target loci in terms of gene expression and regulation;
  • [ENCODE] to modify the function of the target loci to change its expression and regulation for specific goals.

The invitees collectively champion modern -omic approaches that often include precise genome editing (eg CRISPR/Cas9) applied to populations in a high-throughput manner using different strategies (eg lentiviral infections or robotic delivery), tracked in different ways (eg competitive growth assays versus single cell droplet encapsulation), and profiled with -omic and microscopy technologies. Such systematic screens are central to exploring

  • to build codebooks describing interactions between DNA, RNA, protein, and genome struture;
  • to decipher the multivariate biology of higher order genetic and biochemical interactions;
  • to understand the interconnected relationships in systems from ecology, health, and disease;
  • to efficiently optimize systems in the context of synthetic biology.

Emerging Model Systems. January 24th-31st.

This meeting brings together researchers interested in the development of new model organisms. Such models either facilitate exciting new questions that can be asked for the first time, or facilitate unprecedented ability to explore long-standing fundamental questions central to the life sciences. The emergence of many new “non-model” model systems recently is at least in part due to recent advancements in gene editing technologies, cellular imaging, and single cell genomics. Therefore, the workshop also seeks to bring investigators interested in the advancement of such techniques to better exploit the unique biological features of these organisms.

The invitees collectively champion emerging model systems across a broad swath of the Tree of Life. This includes

  • Protist, bacterial and fungal unicellular model systems for studying, for example, carbon sequestration in marine sytems, single cellular regeneration, and genome organization.
  • Individuals who have developed novel models in multicellular organisms including sytems to study regeneration, tissue morphology, and neural function.
  • Researchers with models that may more accurately recapitulate key aspects of human disease in comparison to current systems.
  • Researchers interested in the development of models to study organismal interactions in different environments.
  • Experts in developing synthetic biology, -omics, microscopy and computational/statistical biology approaches to model systems.

SC-SEQ-&-MPRAs

This meeting brings together researchers interested in the development of single cell (SC-Seq) sequencing-based approaches and massively parallel reporter assays (MPRAs), in addition to computational bioogists interested in asking new types of questions facilitated by these technologies in variety of biological systems.

Unless indicated otherwise, the talks are scheduled to be 30 minutes.

Here we focused on the genomic of coral and its microbiome.

OrganizersInstitution
David WalshConcordia University, Canada
Vanessa DumeauxConcordia University, Canada
Mike HallettConcordia University, Canada
Arthi RamachandranConcordia University, Canada
Shawn SimpsonConcordia University, Canada
Kaitlin LavertyUniversity of Toronto, Canada


Invitees Institution
Amy ApprillWoods Hole Oceanographic Institute
John ArchibaldDalhousie University, Canada
Debashish BhattacharyaRutgers University
Rob BeikoDalhousie University, Canada
Stefan BertilssonUppsala University, SciLifeLabs
Erin BertrandDalhousie University, Canada
Adrienne CorreaRice University
Ford DoolittleDalhousie University
Stephen GiovannoniOregon State University
Hans-Peter GrossartLeibniz-Institute of Freshwater Ecology and Inland Fisheries
Lee HenryQueen Mary, University of London
Tim HughesUniversity of Toronto, Canada
Paul JensenScripps, UCSD
Andrew LangMemorial University, Canada
Julie LarocheDalhousie University, Canada
Connie LovejoyUniversite Laval, Canada
Marie-Jean MeursUQAM, Canada
Monica MedinaPennsylvania State University
Adam MonierUniversity of Exeter
Quaid MorrisUniversity of Toronto, Canada
Spencer NyholmUniversity of Conneticut
Martin PolzMIT
Francisco Rodriguez ValeraUniversitas Miguel Hernandez
Andrew RogerDalhousie Univeristy
Forest RohwerSan Diego State University
Daniel SherHaifa University
Derek SkillingsUniversity of Bordeaux/CNRS
Uli StinglUniversity of Florida
Shinichi SunagawaETH Zurich
Adrian TsangConcordia University
Doug WallaceDalhousie University
Harm van BakelMount Sinai
Richard BonneauNYU
David GreshamNYU

Here we focused on the role of the immune system in cancer progression, and on the development of cancer immunotherapies.

Organizers Institution
Therese Sorlie Oslo University Hospital
Vanessa Dumeaux McGill Universiy
Michael Hallett McGill University
Organizing committee
Bjorn Fjukstad The Arctic University of Norway
Silje Nord Oslo University Hospital
Ali Madani Princess Margaret Hospital, U of Toronto
Einar Holsbo The Arctic University of Norway
Allen Zhang University of British Columbia
Invitees
Dana Pe’er Columbia University
Fraser Symmans MD Anderson
Quaid Morris University of Toronto
Jens Lagergren KTH
Benjamin Haibe-Kains Princess Margaret Hospital, U of Toronto
Paul Boutros OICR, U of Toronto
Johan Vallon Christersson Lund University
Jim Lorens University of Bergen
Markus Ringner SciLife Lab
Kalle Malmberg Oslo University Hospital
Daniel De Carvalho UHN, U of Toronto
Joaquim Arribas Vall D’Hebron Insitute of Oncology
Nils Halberg University of Bergen
Juri Reimand OICR, U of Toronto
Pam Ohashi UHN, U of Toronto
Jenn Listgarten Microsoft Research
Brad Nelson BC Cancer Agency
Ole Christian Lingjaerde Oslo University
Andrew McPherson University of British Columbia
Sylvie Mader IRIC, U of Montreal
Bob Clarke Georgetown University
Rejean Lapointe CRCHUM, U of Montreal
John Stagg University of Montreal
Sandra Pommey University of Montreal
E. John Werry University of Pennsylvania
Jonathan Irish Vanderbilt University
Rebecca Ihrie Vanderbilt University
Christos Hatzis Yale University
Celine Laumont IRIC, U of Montreal
Claudia Kleinman Jewish General Hospital and McGill
Etienne Gagnon IRIC, U of Montreal
Mark Basik Jewish General Hospital and McGill
Alex Rubinsteyn Mount Sinai hospital, NY

The focus of this meeting had much of the CCBR-Donnelly in attendance. It was on genetic interaction networks of different types in model organisms.

Organizers Institution
Brenda Andrews University of Toronto
Vanessa Dumeaux McGill University
Mike Hallett McGill University
Organizing committee
Ben Grys University of Toronto
Natasha Pascoe University of Toronto
Dara Lo University of Toronto
Michael Costanzo University of Toronto
Invitees
Fritz Roth University of Toronto
Charlie Boone University of Toronto
Andy Fraser University of Toronto
Brendan Frey University of Toronto
Marian Walhout University of Massachusetts
Malcolm Whiteway Concordia University
Tim Hughes University of Toronto
Alejandro Reyes EMBL, Germany
Olga Troyanskaya Princeton University
Steve Scherer University of Toronto
Mike Tyers IRIC, University of Montreal
Maitreya Dunham University of Washington
Chris Loewen University of British Columbia
Dave Gresham NYU
Doug Fowler U Washington
Jason Moffat University of Toronto
Eric Brown McMaster
Phil Hieter University of British Columbia
Jussi Taipale Karonlinska Institute
Sarah Jenna University of Quebec at Montreal
Jens Lagergren Karolinska University
Mikko Taipale University of Toronto
Kris Gunsalus NYU
Michael Boutros DKFZ
Stirling Churchman Harvard
Lars Steinmetz Stanford
Quaid Morris University of Toronto
Rich Bonneau NYU
Sebastian Nijmen Oxford U
Thijn Brummelkamp Netherland Cancer Institute
Wolfgang Huber EMBL
Gregor Jansen McGill University
Bjorn Fjukstad The Arctic University of Norway

The focus of this meeting was on computational models of tumorigenesis and tumoral evolution, and studies of early breast lesions.

Organizers Institution
Therese SorlieOslo University, Norway
Vanessa DumeauxMcGill University, Canada
Mike HallettMcGill University, Canada
Organizers Institution
Therese Sorlie Oslo University Hospital, Norway
Vanessa Dumeaux McGill University, Montreal, Canada
Mike Hallett McGill University, Montreal, Canada
Organizing Committee
Sadiq Saleh McGill University, Montreal, Canada
Eric Paquet McGill University, Montreal, Canada
Daniel Del Balso McGill University, Montreal, Canada
Jens Henrik Norum Oslo University Hospital, Norway
Tina Gruosso McGill University, Canada
Paul Savage McGill University, Canada
Invitees
Piyush Gupta Whitehead Institute, Boston, USA
Charlotte Kuperwasser Tufts University, Boston, USA
Jorge Reis-Filho Memorial Sloan-Kettering, NY, USA
Fraser Symmans MD Anderson, Texas, USA
Christopher Greenman University of East Anglia, UK
Florian Markowetz University of Cambridge, UK
Rene Villadsen The Danish Stem Cell Center
Nicholas Navin MD Anderson, Texas, USA
Nicholas McGranahan Swanton Lab, London Research Institute, UK
Carlo Maley UCSF, USA
C Athena Aktipis UCSF, Arizona
Þórarinn Guðjónsson University of Iceland, Iceland
Niko Beerenwinkel ETH-Zuerich, Switzerland
Andrew Beck Dana-Farber, Harvard Cancer Centre, USA
Robert Clarke Georgetown University, Washington DC, USA
Alexander RA Anderson Moffit Cancer Centre, Florida, USA
Yuval Kluger Yale, CT, USA
Alexandre Bouchard-Cote UBC, Vancouver, Canada
Mark Basik Lady Davis Institute, McGill University
Adriana Aguilar Lady Davis Institute, McGill University
Gunhild Mælandsmo Oslo University Hospital, Norway
Kristin Andersen Oslo University Hospital, Norway
Jim Lorens University of Bergen, Norway
Quaid Morris University of Toronto, Canada
Benjamin Haibe-Kains Princess Margaret Hospital, Toronto, Canada
Paul Boutros OICR, Toronto, Canada
Sohrab Shah BCCA, Vancouver, Canada
Lars Ailo Bongo UiT Artic University of Norway
Uri David Akavia McGill, Montreal, Canada
Silje H. Nord Oslo University Hospital, Norway
Nicholas Bertos McGill, Montreal, Canada
Jens Lagergren SciLifeLab & KTH, Stockholm, Sweden
Mark Labarge Berkeley Laboratory, USA
Zohar Yakhini Israel Institute of Technology, Israel
Gary Bader CCBR, University of Toronto
Sylvie Mader IRIC; Université de Montréal
Celia Greenwood Jewish General Hospital; McGill
Ingrid Hedenfalk Lunds universitet
Christos Hatzis Yale University
Ben J. Raphael Brown University

This meeting brought down many members of the international microRNA community wheree we discussed research, current challenges and the way onward.

Organizers Institution
Thomas DuchaineMcGill University, Canada
Vanessa DumeauxMcGill University, Canada
Mike HallettMcGill University, Canada
Invitees Institution
Julie PellouxUniversite de Montreal
Chris HillierUniversity of the West Indies
Ali TofighMcGill University
Frank SlackYale UniversityMicroRNA-based therapeutics in cancer
Brenda AndrewsUniversity of TorontoUsing yeast functional genomics to explore biological pathways and non-coding RNA function
Eric LaiMemorial Sloan-Kettering Cancer CenterMicroRNAs and other post-transcriptional regulation
Jens LagergrenSciLifeLab Stockholm
Marie ÖhmanStockholm UniversityRegulation of miRNAs by RNA editing in neurons
Chris HammellCold Spring Harbor LaboratoryTemporal regulation of miRNA expression during C. elegans post-embryonic development
Ren&eacute KettingInstitute of Molecular Biology (IMB)Diversity of small RNA pathways in germ cells
Colin CristMcGill UniversityPost-transcriptional mechanisms regulating skeletal muscle stem cell activity
Martin SimardLaval University Cancer Research CenterUnderstanding small RNA pathways through the Argonautes
Marc FabianLady Davis Institute for Medical ResearchInsights into recruitment of the CCR4-NOT complex by mammalian gene silencing platforms
Amy PasquinelliUC San DiegoThe multifaceted miRISC
Helge GrosshansFriedrich Miescher Institute for Biomedical ResearchTowards a quantitative understanding of miRNA function and regulation in physiology
Antonio GiraldezYale UniversityUsing ribosome footprinting to analyze the coding genome
Eric MiskaGurdon InstituteC. elegans piRNAs
Nada JabadoMcGill UniversityFusion of TTYH1 with the C19MC microRNA cluster in the embryonal brain tumor ETMR
Tim HughesUniversity of TorontoExploring the universe of RNA-binding proteins
Sohail TavazoieThe Rockefeller UniversitymicroRNAs as molecular probes into the biology of metastasis
Nikolaus RajewskyMax Delbruck Center for Molecular MedicineRNA-protein interactions
Richard CarthewNorthwestern UniversityMicroRNAs in Drosophila
Hin Hark GanNew York University3D Modeling of miRISC-Target Interactions
Yifei YanUniversite de MontrealDesigning small artificial miRNAs to inhibit HIV production
Paul BoutrosOntario Institute for Cancer Research (OICR)miRNA-Based Biomarkers for Cancer: Challenges & Successes
Nathanael WeillUniversite de MontrealModeling miRNA-induced gene expression regulation
Lill-Tove BusundUniversitetet i TromsøDetection of microRNA in tissue blocks or MicroRNA in the clinic
Line MoiUniversity hospital of North NorwaylmicroRNAs as biomarkers in breast cancer
Francois MajorUniversite de MontrealRNA transient structures control the microRNA maturation pathway
Ahilya SawhMcGill UniversityThe post-translational life of DCR-1
Ariel DonayoMcGill UniversityRegulation of the maturation of pri-miR-17~92 in normal and cancer cells
Mathieu FlamandMcGill UniversityA non-canonical site reveals multiple cooperative mechanisms in microRNA-mediated silencing

This meeting focused on the development of genomics-based approaches for the identification and implementation of biomarkerss for patient prognosis and benefit to therapy.

Organizers Institution
Mike HallettMcGill University, Canada
Vanessa DumeauxMcGill University, Canada
Sylvie MaderUniversite de Montreal, Canada
Invitees Institution
Justyna KulpaUniversite de MontrealEndocrinology
Uri David AkaviaColumbia UniversityComputational Systems Biology
David Cotnoir-WhiteUniversite de MontrealMolecular Oncology
Quaid MorrisUniversity of Toronto, CanadaComputational Biology
Trevor LevinOHSU Knight Cancer Institute, OregonCancer Genomics
Sandra Krum-HansenUniversity of TromsoEpidemiology
Luke McCaffreyMcGill University, CanadaMolecular Oncology
Veena SangwanUniversity of MinnesotaMolecular Oncology
Jennifer KnightUniversite de MontrealMolecular Oncology
Wilbert ZwartUniversite de MontrealMolecular Oncology
Eric PaquetMcGill University, CanadaComputational Biology
John OzcelikMcGill University, CanadaComputational Biology
Sadiq SalehMcGill University, CanadaCancer Genomics
Matthew SudermanMcGill University, CanadaComputational Biology
Ali TofighMcGill University, CanadaComputational Biology
Robert LesurfMcGill University, CanadaComputational Biology
Sean CoryMcGill University, CanadaComputational Biology
Julie LivingstoneMcGill University, CanadaComputational Biology
Harvey SmithMcGill University, CanadaMolecular Oncology
Genevieve DebloisMcGill University, CanadaMolecular Oncology
Jose TeodoroMcGill University, CanadaMolecular Oncology
Lodewyk WesselsUniversite de MontrealComputational Biology
Mathieu LupienUniversite de MontrealMolecular Oncology
Nicholas BertosMcGill University, CanadaMolecular Oncology
Morag ParkMcGill University, CanadaMolecular Oncology
Vincent GiguereMcGill University, CanadaMolecular Oncology
Thomas DuchaineMcGill University, CanadaMolecular Oncology
David JunckerMcGill University, CanadaMicrofluidics
Therese SorlieRadition Hopsital, OsloBreast Cancer Genomics
Eiliv LundUniversite de MontrealEpidemiology
Marc ZapatkaUniversite de MontrealCancer Genomics and Bioinformatics
Benjamin Haibe-KainsUniversite de MontrealComputational Biology
Steve JonesUniversite de MontrealGenomics
Janusz RakMcGill University, CanadaMolecular Oncology
Simak AliImperial College School of Medicine, LondonMolecular Oncology
Josie DostieMcGill University, CanadaMolecular Oncology
Paul BoutrosOntario Institute for Cancer Research, CanadaCancer Informatics
Stephen M. RobbinsSouthern Alberta Cancer Research Institute, CanadaExtracellular signalling in Cancer
Richard SimonNational Cancer Institute, USACancer Treatment and Diagnosis

This meeting focused on transcription factors, protein-DNA binding and the complex network of regulatory dependencies they induce.

Organizers Institution
Mike HallettMcGill University, Canada
Tim HughesUniversity of Toronto, Canada
Organizers Institution
Brenda AndrewsUniversity of Toronto, CanadaYeast network biology
Phil BenfeyDuke University, USAGene expression in Arabidopsis
Kris GunsalusNew York University, USAC. elegans functional genomics and post-transcriptional regulation
Henry KrauseUniversity of Toronto, Canadatranscriptional and post-transcriptional regulation in Drosophila and zebrafish
Jason LiebUNC Chapel Hill, USAFunctional genomics, gene regulation, and chromatin
Howard LipshitzUniversity of Toronto, Canadaposttranscriptional regulation of gene expression in Drosophila
Don MoermanUniversity of British Columbia, CanadaBasic genetics, transposon biology, genetic methodology, genomics and muscle development in Caenorhabditis elegans
Quaid MorrisUniversity of Toronto, CanadaComputational biology
Corey NislowUniversity of Toronto, CanadaSystems biology
Fabio PianoNew York University, USASystems biology, C. elegans embryogenesis
Eran SegalWeizmann Institute, IsraelComputational biology
Craig SmibertUniversity of Toronto, CanadaRegulation of translation
Jussi TaipaleKarolinska Institutet, SwedenRNAi screening, identification of transcriptional regulatory mechanisms, and identification of the sequence specificities of DNA-binding proteins
Charles VinsonNational Institutes of Health, USApromoter analysis, transcription factors, DNA methylation
Bob WaterstonUniversity of Washington, USAGenome science
Lisa StubbsUniversity of Illinois, USAC2H2 zinc finger transcription factors
Nick LuscombeEBI, UKComputational biology
Alain NepveuMcGill University, CanadaTranscriptional regulation in mammalian cells
Matt WeirauchUniversity of Toronto, CanadaComputational methods for transcription regulation
Anna LeeUniversity of Toronto, Canada
Kate CookUniversity of Toronto, Canada
Hilal KazanUniversity of Toronto, Canada
Xiao LiUniversity of Toronto, Canada
Guillaume BourqueMcGill University and Genome Quebec Innovation Center, Canada
Jens LagergrenScience for Life Laboratory, Sweden
Susanne GroebnerUniversity of Heidelberg, Germany
Benjamin BoucherUniversity of Quebec in Montreal, Canada

The central topic of this meeting was to explore the use of techniques from systems biology including high-throughput profiling, modelling and multivariate biomarker panels in the context of breast cancer.

Organizers Institution
Mike HallettMcGill University, Canada
Vanessa DumeauxUniversity of Tromso, Norway
ParticipantsAffiliationExpertise
Nicholas BertosMcGill University, CanadaGenomics
Margarethe BiongOslo University Hospital, NorwayGenomics
Sean CoryMcGill University, CanadaBioinformatics
Slim FouratiUniversite de Montreal, CanadaGenomics
Gregor JansenMcGill University, CanadaCell Signaling
Vessela KristensenOslo University Hospital, NorwayGenomics
Hege Landmark-HoyvikOslo University Hospital, NorwayGenomics
Robert LesurfMcGill University, CanadaBioinformatics
Julie LivingstoneMcGill University, CanadaBioinformatics
Joseph LucasDuke University, USABioinformatics
Sylvie MaderUniversite de Montreal, CanadaGenomics
Hans-Kristian Moen-VollanOslo University Hospital, NorwaySurgeon; Genomics
William MullerMcGill University, CanadaMolecular Oncology
Morag ParkMcGill University, CanadaMolecular Oncology
Sandra Caroline PlancadeUniversity of Tromso, NorwayStatistics
Irene PylypenkoMcGill University, CanadaBioinformatics
Hege RussnessHarvard University, USABreast Cancer
Derek RuthsMcGill University, CanadaBioinformatics
Cenk SahinalpSimon Fraser University, CanadaComputational Genomics
Sadiq SalehMcGill University, CanadaBioinformatics
Babette SchadeMcGill University, CanadaMolecular Oncology
Bita SehatMcGill University, CanadaMolecular Oncology
Sohrab ShahUniversity of British Columbia, CanadaBioinformatics
Peter SiegelMcGill University, CanadaMolecular Oncology
Matthew SudermanMcGill University, CanadaBioinformatics
David ThomasMcGill University, CanadaOther
Christina TognonUniversity of British Columbia, CanadaBreast Cancer
Ali TofighMcGill University, CanadaBioinformatics
Braaten TonjeUniversity of Tromso, NorwayEpidemiology
Josie Ursini-SiegelUniversite de Montreal, CanadaMolecular Oncology
Johan Vallon-ChristerssonLund University, SwedenBC Susceptibility Genes
John WhiteMcGill University, CanadaGenomics
</tr> </table>
Organizers Institution
Mike HallettMcGill University
Sarah JennaUniversité de Québec à Montréal
David ThomasMcGill University
Invitees
Brenda AndrewsUniversity of TorontoStudy of cell cycle and cell division in budding yeast
Suzana AnjosMcGill UniversityCystic fibrosis, response-to-chemical gene expression signatures
Bill BalchThe Scripps Research InstituteProtein trafficking and misfolding disease
Margarethe BiongNorwegian Radium HospitalAssociations between genotype profiles and breast cancer risk factors
Rich BonneauNew York UniversityPeptide design
Fabiana CicirielloMcGill UniversityCystic fibrosis, response-to-chemical gene expression signatures
Vanessa DumeauxUniversity of TromsoEpidemiology of Environmental Exposures in Cancer
Elias EppMcGill UniversityFungal genomics, antifungal synergy
Guri GiaeverUniversity of TorontoChemical genomics
Sara JC GoslineMcGill UniversityProbabilistic models of endoplasmic reticulum quality control
Gregor JansenMcGill UniversityChemogenomic profiling, antifungal synergy
Danielle KemmerMcGill UniversityThe study of orphan diseases via chemical genomics
Hege BK Landmark-HøyvikNorwegian Radium HospitalBlood gene expression to investigate response to and late side effects of radiotherapy
Anna Y LeeMcGill UniversityPredicting antifungal synergy and therapeutic targets for genetic disorders
Sébastien LemieuxUniversité de MontréalFunctional and structural bioinformatics
Nicolas MoitessierMcGill UniversityChemo-informatics
Corey NislowUniversity of TorontoChemical genomics
Dana Pe'erColumbia UniversityComputational systems biology
Lekha SlenoUniversité de Québec à MontréalMetabolome, drug metabolism and mass spectrometry
Jérome WaldispühlMcGill UniversityPredicting the structures of proteins and RNAs
Dan ZilbersteinTechnion - Israel Institute of TechnologyLeishmaniasis

This meeting focused on genomics approaches in breast cancer to study both murine models and the human disease.

Organizers Institution
Mike HallettMcGill University
Morag ParkMcGill University
Invitees
Jørgen AarøeRikshospitalet Institute for Cancer ResearchGenomic alterations and systemic changes in early breast cancer.
Nicholas BertosMcGill UniversityDTCs/CTCs in breast cancer.
Sean CoryMcGill UniversityBioinformatics of breast cancer.
Rachelle DillonMcGill UniversityErbb2 mouse models of breast cancer.
Vanessa DumeauxRikshospitalet Institute for Cancer Research/PrincetonBreast density, epidemiology.
Slim FouratiUniversity of MontrealEstrogen positive breast cancer.
Kalle GehringMcGill UniversityStructural biology, endocytosis.
Vincent GiguèreMcGill UniversityReceptor signaling in breast cancer.
Kun HuangOhio State UniversityBioinformatics of cancer.
Gregor JansenMcGill UniversityCell signaling pathways.
Jennifer KnightMcGill UniversityMet mouse models of breast cancer.
Julie LaferrièreMcGill UniversityMetastases and the microenvironment in breast cancer.
Gustavo LeoneOhio State UniversityBreast tumor microenvironment.
Robert LesurfMcGill UniversityBionformatics in breast cancer.
Jason MadoreUniversity of MontrealTissue microarrays for ovarian cancer.
Anne-Marie Mes-MassonUniversity of MontrealIdentification and characterization of expression patterns in cancer progression.
Aslaug Aamodt MuggerudRikshospitalet Institute for Cancer ResearchDCIS in breast cancer.
William MullerMcGill UniversityRole of the Epidermal Growth Factor Receptor (EGFR) family in the induction and progression of breast cancer.
Alain NepveuMcGill UniversityCDP/Cux.
Michael OstrowskiOhio State UniversityBreast tumor microenvironment.
Jeff ParvinOhio State UniversityThe biology of BRCA1.
François PepinMcGill UniversityMicroenvironment in breast cancer.
Jill RangerMcGill UniversitySTAT3.
Maya SalehMcGill UniversityApoptosis, inflammation and host response to infections.
Babette SchadeMcGill UniversityMouse models of meastases.
Solmaz ShahahlizadehMcGill UniversityMetapredictors in breast cancer.
Peter SiegelMcGill UniversityBreast cancer metastases to bone and soft tissues.
Sebastien TabariesMcGill UniversityBreast cancer metastases.
David ThomasMcGill UniversityCell signaling pathways and their role in infectious diseases; molecular chaperone systems in the endoplasmic reticulum.
Josie Ursini-SiegelMcGill UniversityErbb2 mouse models of breast cancer.
Charles VadnaisMcGill UniversityChIP-Chip/transcription in breast cancer.

The invitees discusssed protein-protein, genetic and chemical-genetic interactions in both model organsisms and humans.

Organizers Institution
Mike HallettMcGill University
Sarah JennaUniversité de Québec à Montréal
Invitees
Brenda AndrewsDonnelly CCBR, University of TorontoYeast functional genomics, cell cycle
Richard BonneauBiology/Computer Science, NYURegulatory network inference, de novo structure prediction
Charlie BooneBBDMR, Donnelly CCBR, University of TorontoYeast genetic interactions, chemical genomics
Benedikt BrorsTheoretical Bioinformatics, German Cancer Research Center (DKFZ)Cancer biology, gene expression analysis
Jenny BryanStatistics, University of British ColumbiaStatistical genomics
Susan CelnikerLawrence Berkeley National LaboratoryTranscription networks and protein complexes in Drosophila
Xavier de BolleMolecular Biology, University of Namur FUNDPBrucella melitensis virulence, inter-species interactions
Denis DupuyCCSB, DCFI, Harvard Medical SchoolC. elegans promoterome
Andrew FraserWellcome Trust Sanger InstituteSignal transduction, genetic interactions in C. elegans
Guri GiaeverDonnelly CCBR, University of TorontoChemical genomics
Sara GoslineMCB, McGill UniversityIntegrative bioinformatics for ER quality control studies, proteomics
Kris GunsalusBiology, New York UniversityIntegrating and mining functional genomics data, C. elegans
Tim HughesBBDMR, Donnelly CCBR, University of TorontoFunctional genomic units, DNA-binding, RNA processing in yeast and mouse
Gregor JansenBiochemistry, McGill UniversityChemical genomics, cell signaling, endoplasmic reticulum
Anna LeeMCB, McGill UniversityIntegrative bioinformatics for chemical genomics, C. elegans genetic interactions
Edward MarcotteCSSB, ICMB, University of TexasProtein function and interaction informatics
Stephen MichnickBiochemistry, Université de MontréalBiochemical and genetic networks, HTP protein interaction studies
Corey NislowBBDMR, Donnelly CCBR, University of TorontoNucleosome occupancy, chemical genomics
Tony PawsonSLRI, University of TorontoSignal transduction
Fabio PianoBiology, NYUFunctional genomics, early embryogenesis in nematodes
Jérôme ReboulFunctional Genomics, Marseilles Cancer Research Center, INSERMMolecular networks implicated in epithelial polarity, C. elegans
Fritz RothCCSB, Biological Chemistry and Molecular Pharmacology, Harvard Medical Schoolgenetic pathways, alternative splicing, integration informatics
Igor StagljarDonnelly CCBR, University of TorontoProtein-protein interactions, drug discovery, genome stability
David ThomasBiochemistry, McGill UniversityChemical genomics, cell signaling, endoplasmic reticulum
Christine VogelCSSB, ICMB, University of TexasBioinformatics for genome evolution, protein expression
AJ Marian WalhoutMolecular Medicine, Gene Function and Expression, UMass Medical SchoolTranscription regulatory circuits in C. elegans
Monique ZetkaBiology, McGill UniversityMeiosis in C. elegans

This meeting brought together researchers interested in understanding how genomic instability, and the evolution of neoplastic genomes, affects cancer progression.

Organizers Institution
Mike HallettMcGill University
Jens LagergrenStockholm Bioinformatics Centre
Ben RaphaelUniverisity of California, San Diego
ParticipantsAffiliationExpertise
Ake BorgLund Stem Cell CenterGenomic alterations/gene expression in breast tumors
Collin CollinsUCSF Cancer CenterGenomic instability
Greg FinakMCB, Biochemistry, McGill UniversityBreast Cancer Gene Expression
William MullerMolecular Oncology, McGill UniversityHer2/neu mouse models of breast cancer
Alain NepveuBiochemistry, Molecular Oncology, McGill UniversityTranscriptional regulation, cancer
Morag ParkBiochemistry, Molecular Oncology, McGill UniversityReceptor tyrosine kinases, Met, Breast Cancer
Francois PepinMCB, Biochemistry, McGill UniversityBreast Cancer Gene Expression
Babette SchadeMolecular Oncology, McGill UniversityHer2/neu mouse models of breast cancer
Peter SiegelMedicine, McGill UniversityBreast cancer metastasis
Cristina TognonChild and Family Research Institute, UBCBreast cancer, fusion proteins
Nicholas BertosBCFGG, McGill UniversityManager, BC functional genomics platform
Jacqueline HallMOG/MCB, McGill UniversityPostdoc, Biostatistics
April RoseMedicine, McGill UniversityBone Mets, BC
Marisa PonzoBiochemistry, McGill UniversityMet mouse models
Sean CoryMCB, McGill UniversityBioinformatics
Robert LesurfMCB, McGill UniversityBioinformatics, Mouse Models
Indrani AttiganalMCB, McGill UniversityManager, BC Bioinformatics

This meeting brought together researchers interested in diseases of the secretory pathway with special emphasis on the endoplasmic reticulum

</tr> </table>
Organizers Institution
Michael Hallett Bioinformatics, McGill Bioinformatics
Christina Haston Dept. of Medicine, McGill Cystic Fibrosis
David ThomasBiochemistry, McGillER/Chemicogenomics
Participant Affiliation Specialty
Sara Calafell Bioinformatics, McGill </td> Models of the ER
Eric Chevet Cell Biology/Surgery, McGill C.Elegans, UPR
Daniela Cernea Bioinformatics, McGill Bioinformatics
Lane Clarke University of Missouri Cystic Fibrosis
Sean Cory Bioinformatics, McGill Bioinformatics/Cystic Fibrosis
Lars Ellgaard Biochemistry, ETH Zuerich ER/Protein Folding
Nir Friedman Computational Biology, Hebrew University Models of biological systems
Kalle Gehring Biochemistry, McGill Structural Biology
John Hanrahan Physiology, McGill Cystic Fibrosis
Gregor Jansen Biochemistry, McGill ER
Sarah Jenna Montreal Proteomics Network, McGill C. Elegans, UPR
Martin Latterich Anatomy/Cell Biology, McGill Organelle Biogenesis
Michal Linial Biological Chemistry, Hebrew University Secretory system
Susan Lindquist Whitehead/MIT Stress response/chaperones
Gergely Lukacs Sick Kids Research, Univ. of Toronto CFTR
Al Shrier Physiology, McGill HERG
Malcolm Whiteway NRC-BRI Chemical Genomics

This was the first of our Barbados meetings to focus on breast cancer.

</tr> </table>
Organizers Institution
Michael Hallett Bioinformatics, McGill Bioinformatics
Morag Park Oncology, Biochem, Medicine, McGill Breast Cancer
Participant Affiliation Specialty
T. Brown U. of Toronto Microrrays
J. Bryan Statistics, UBC Microrrays
H. Chen Mol. Oncology, McGill LCM, Microarrays
G. Finak Biochemistry, McGill Bioinformatics
A. Filali Inst. du cancer, U. de Mont. Bioinformatics
I. Jurisica U. of Toronto Bioinfo/Ovarian Cancer </tr>
B. Muller Mol. Oncology, McGill Her2 Mouse Models
F. Pepin Bioinformatics, McGill Bioinfo/TGF-Beta
S. PetkiewiczOncology, Biochem, Medicine, McGill Met, Breast Cancer </tr>
B. SchadeMol. Oncology, McGill Her2 Mouse Models
P. SiegelMedicine, McGill TGF-Beta/Neu
D. ThomasBiochemistry, McGill Chemical Genomic Screens
C. Tognon BCRI, UBC Fusion Proteins
Z. YakhiniAgilent Microarrays
J. WulfkuhleCenter for Cancer Research, NCI Proteomics/Breast Cancer

Our second Barbados workshop focused on the development of algorithms for identifying transcription factor binding sites.


Organizers Institution
Michael Hallett McGill University, Canada Mathieu Blanchette McGill University
Jens Lagergren Stockholm Bioinformatics Centre, Sweden David Bryant McGill University
Harmen Bussemaker Columbia
Alessandro Panconesi La Sapienza di Roma, Italy
Tzachi Pilpel Harvard
Gary Stormo Washington University
Martin Tompa University of Washington
Wyeth Wasserman UBC, Canada
Kaleigh Smith McGill University
      Lee Ann McCue Wadsworth Centre, NYS Dept. of Health
Markus Jalsensius McGill University

Our first Barbados workshop focused on the development of algorithms for exploring genome evolution.


Organizers Institution
Michael Hallett McGill University, Canada   Benny Chor Technicon, Israel
Jens Lagergren Stockholm Bioinformatics Centre, Sweden

 

Tandy Warnow University of Texas at Austin, U.S.A.
  Todd Wareham Memorial University of Newfoundland, Canada
  Pavel Pevzner University of Southern California, U.S.A.
  Alberto Caprara Universitš di Bologna, Italy
      Allessandro Panconesi Universitš La Sapienza di Roma, Italy
      Nadia El-Mabrouk Universite de Montreal, Canada
      David Bryant McGill University, Canada
      Bernard Moret University of New Mexico, U.S.A.
      Louigi Addario-Berry McGill University, Canada